Scientists are racing to develop three new vaccines against the rare Bundibugyo species of Ebola, which has already killed nearly 250 people in DR Congo. With over 1,000 suspected cases and spread into Uganda, experts warn this outbreak detected late in a conflict zone could rival the devastating 2014-16 West Africa epidemic.

Nipah Virus Infection: Nipah virus causes severe respiratory illness and encephalitis with high fatality rates. Transmitted from animals (especially bats and pigs) to humans and between people, it remains a major concern due to its epidemic potential. No widely available licensed vaccine exists.

Lassa Fever: Lassa fever is a viral hemorrhagic disease spread mainly through contact with infected rodents. It can cause fever, bleeding, and organ failure. Endemic in parts of West Africa, it has significant outbreak potential. No widely available licensed vaccine.

Marburg Virus Disease: Marburg virus causes severe hemorrhagic fever with high case fatality rates. Similar to Ebola, it spreads through contact with infected bodily fluids or bats. Outbreaks can escalate quickly. No widely available licensed vaccine exists.

Crimean-Congo Hemorrhagic Fever: Crimean-Congo Hemorrhagic Fever is a tick-borne viral disease that can cause severe bleeding and organ failure. It spreads easily in healthcare settings. Found in parts of Africa, Europe, and Asia, it poses a serious threat. No widely available licensed vaccine.

Hantavirus Pulmonary Syndrome: Hantavirus Pulmonary Syndrome leads to severe respiratory distress and can be fatal. Transmitted through contact with infected rodent droppings or urine, it causes sudden, life-threatening lung issues. No widely available licensed vaccine exists.

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): MERS-CoV causes severe respiratory illness with high mortality. It spreads from camels to humans and between people. First identified in the Middle East, it continues to pose outbreak risks. No widely available licensed vaccine.

Zika Virus: Zika virus is spread primarily by mosquitoes and can cause birth defects if contracted during pregnancy. It also leads to neurological complications in adults. Outbreaks remain a concern in tropical regions. No widely available licensed vaccine.

Disease X: Disease X represents a currently unknown pathogen capable of causing a serious international epidemic. Experts prepare for this unknown threat, which could emerge from wildlife or other sources with pandemic potential. No vaccine exists by definition.
